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A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors

Using molecular modeling approach, potential antibacterial agents with triazole core were proposed. A moderate to weak level of antibacterial activity in most of the compounds have been observed, with best minimal inhibitory concentration (MIC) value of 0.003 mg/mL, as shown by the 15 against S. epi...

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Vydáno v:Molecules
Hlavní autoři: Paneth, Agata, Frączek, Tomasz, Grzegorczyk, Agnieszka, Janowska, Dominika, Malm, Anna, Paneth, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150362/
https://ncbi.nlm.nih.gov/pubmed/29068373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111808
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