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What do docking and QSAR tell us about the design of HIV-1 reverse transcriptase nonnucleoside inhibitors?

Despite vigorous studies, effective nonnucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs) are still in demand, not only due to toxicity and detrimental side effects of currently used drugs but also because of the emergence of multidrug-resistant viral strains. In this contribution, we pre...

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Detaylı Bibliyografya
Yayımlandı:J Mol Model
Asıl Yazarlar: Paneth, Agata, Płonka, Wojciech, Paneth, Piotr
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655543/
https://ncbi.nlm.nih.gov/pubmed/29046967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-017-3489-3
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