New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking

Sortase A inhibition is a well establish strategy for decreasing bacterial virulence by affecting numerous key processes that control biofilm formation, host cell entry, evasion and suppression of the immune response and acquisition of essential nutrients. A meta-analysis of structures known to act...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Oniga, Smaranda Dafina, Araniciu, Cătălin, Palage, Mariana Doina, Popa, Marcela, Chifiriuc, Mariana Carmen, Marc, Gabriel, Pirnau, Adrian, Stoica, Cristina Ioana, Lagoudis, Ioannis, Dragoumis, Theodoros, Oniga, Ovidiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150342/
https://ncbi.nlm.nih.gov/pubmed/29077016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111827
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