Hepatotoxicity Induced by Sophora flavescens and Hepatic Accumulation of Kurarinone, a Major Hepatotoxic Constituent of Sophora flavescens in Rats

Our previous study showed that kurarinone was the main hepatotoxic ingredient of Sophora flavescens, accumulating in the liver. This study characterized the mechanism of Sophora flavescens extract (ESF) hepatotoxicity and hepatic accumulation of kurarinone. ESF impaired hepatic function and caused f...

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Bibliographic Details
Published in:Molecules
Main Authors: Jiang, Peng, Zhang, Xiuwen, Huang, Yutong, Cheng, Nengneng, Ma, Yueming
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150336/
https://ncbi.nlm.nih.gov/pubmed/29068394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111809
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