Influence of Shenxiong Glucose Injection on the Activities of Six CYP Isozymes and Metabolism of Warfarin in Rats Assessed Using Probe Cocktail and Pharmacokinetic Approaches

Shenxiong glucose injection (SGI), a traditional Chinese medicine (TCM) preparation, has been widely used for the treatment of various cardiovascular and cerebrovascular diseases for many years. We assessed the potential influences of SGI on the activities of six CYP enzymes (CYP1A2, CYP2C11, CYP2C1...

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Udgivet i:Molecules
Main Authors: Sun, Jia, Lu, Yuan, Li, Yueting, Pan, Jie, Liu, Chunhua, Gong, Zipeng, Huang, Jing, Zheng, Jiang, Zheng, Lin, Li, Yongjun, Liu, Ting, Wang, Yonglin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150296/
https://ncbi.nlm.nih.gov/pubmed/29156621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111994
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