Antibacterial Activity of the Non-Cytotoxic Peptide (p-BthTX-I)(2) and Its Serum Degradation Product against Multidrug-Resistant Bacteria

Antimicrobial peptides can be used systemically, however, their susceptibility to proteases is a major obstacle in peptide-based therapeutic development. In the present study, the serum stability of p-BthTX-I (KKYRYHLKPFCKK) and (p-BthTX-I)(2), a p-BthTX-I disulfide-linked dimer, were analyzed by ma...

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Publicado no:Molecules
Main Authors: Santos-Filho, Norival A., Fernandes, Rafaela S., Sgardioli, Bruna F., Ramos, Matheus A. S., Piccoli, Julia P., Camargo, Ilana L. B. C., Bauab, Tais M., Cilli, Eduardo M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150245/
https://ncbi.nlm.nih.gov/pubmed/29113051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111898
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