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Inhibition of Human Kallikrein 5 Protease by Triterpenoids from Natural Sources

Stratum corneum tryptic enzyme kallikrein 5 (KLK5) is a serine protease that is involved in the cell renewal and maintenance of the skin barrier function. The excessive activation of KLK5 causes an exacerbation of dermatoses, such as rosacea and atopic dermatitis. Some triterpenoids are reported to...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Matsubara, Yosuke, Matsumoto, Takashi, Koseki, Junichi, Kaneko, Atsushi, Aiba, Setsuya, Yamasaki, Kenshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150226/
https://ncbi.nlm.nih.gov/pubmed/29077044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22111829
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