Glucuronides of phytoestrogen flavonoid enhance macrophage function via conversion to aglycones by β‐glucuronidase in macrophages

INTRODUCTION: Flavonoids are converted to inactive metabolites like glucuronides in the gut, and circulate mainly as glucuronides in blood stream, resulting in low concentrations of active aglycones in plasma. It is therefore unclear how oral flavonoids exert their effects in tissues. We recently re...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Kaneko, Atsushi, Matsumoto, Takashi, Matsubara, Yosuke, Sekiguchi, Kyoji, Koseki, Junichi, Yakabe, Ryo, Aoki, Katsuyuki, Aiba, Setsuya, Yamasaki, Kenshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569364/
https://ncbi.nlm.nih.gov/pubmed/28480538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.163
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