Glucuronides of phytoestrogen flavonoid enhance macrophage function via conversion to aglycones by β‐glucuronidase in macrophages

INTRODUCTION: Flavonoids are converted to inactive metabolites like glucuronides in the gut, and circulate mainly as glucuronides in blood stream, resulting in low concentrations of active aglycones in plasma. It is therefore unclear how oral flavonoids exert their effects in tissues. We recently re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Immun Inflamm Dis
Prif Awduron: Kaneko, Atsushi, Matsumoto, Takashi, Matsubara, Yosuke, Sekiguchi, Kyoji, Koseki, Junichi, Yakabe, Ryo, Aoki, Katsuyuki, Aiba, Setsuya, Yamasaki, Kenshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569364/
https://ncbi.nlm.nih.gov/pubmed/28480538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.163
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