Effect of oral fluconazole 1200 mg/day on QT interval in African adults with HIV-associated cryptococcal meningitis

We assessed the effect of fluconazole 1200 mg/day on the QT interval in cryptococcal meningitis patients. Mean corrected QT (QTc) change from baseline to day 7 was 10.1 ms (IQR: −28 to 46 ms) in the fluconazole treatment group and −12.6 ms (IQR: −39 to 13.5 ms) in those not taking fluconazole (P = 0...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Molloy, Síle F., Bradley, John, Karunaharan, Natasha, Mputu, Muhammad, Stone, Neil, Phulusa, Jacob, Chawinga, Chimwemwe, Gaskell, Kate, Segula, Dalitso, Ming, Damien, Peirse, Mary, Chanda, Duncan, Lakhi, Shabir, Loyse, Angela, Kanyama, Cecilia, Heyderman, Robert S., Harrison, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Research Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150187/
https://ncbi.nlm.nih.gov/pubmed/30102652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001961
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