HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells

Ovarian cancers are known to evade immunosurveillance and to orchestrate a suppressive immune microenvironment. Here we examine the role of human epididymis protein 4 (HE4), an ovarian cancer biomarker, in immune evasion. Through modified subtractive hybridization analyses we have characterized the...

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Publicat a:Clin Exp Immunol
Autors principals: James, N. E., Cantillo, E., Oliver, M. T., Rowswell‐Turner, R. B., Ribeiro, J. R., Kim, K.‐K., Chichester, C. O., DiSilvestro, P. A., Moore, R. G., Singh, R. K., Yano, N., Zhao, T. C.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149960/
https://ncbi.nlm.nih.gov/pubmed/29745428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13153
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