Human Epididymis Secretory Protein 4 (HE4) Compromises Cytotoxic Mononuclear Cells via Inducing Dual Specificity Phosphatase 6

While selective overexpression of serum clinical biomarker Human epididymis secretory protein 4 (HE4) is indicative of ovarian cancer tumorigenesis, much is still known about the mechanistic role of the HE4 gene or gene product. Here, we examine the role of the secretory glycoprotein HE4 in ovarian...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: James, Nicole E., Oliver, Matthew T., Ribeiro, Jennifer R., Cantillo, Evelyn, Rowswell-Turner, Rachael B., Kim, Kyu-Kwang, Chichester, Clinton O., DiSilvestro, Paul A., Moore, Richard G., Singh, Rakesh K., Yano, Naohiro, Zhao, Ting C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433991/
https://ncbi.nlm.nih.gov/pubmed/30941033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00216
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