Preparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 cells

BACKGROUND: Honokiol is a bioactive lignanoid and has been utilized in traditional Chinese medicine for a long time. It exhibits several pharmacological properties, such as anticancer effects, anti-inflammatory effects, and antianxiety effects. However, the poor aqueous solubility of honokiol has im...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Nanomedicine
Prif Awduron: Wu, Weiwei, Wang, Li, Wang, Lingling, Zu, Yuangang, Wang, Siying, Liu, Peiyan, Zhao, Xiuhua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149943/
https://ncbi.nlm.nih.gov/pubmed/30271141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S178416
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