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Cell fate in colon cancer stem cells: To GLI or not to GLI?(*)
Colon cancer is a heterogeneous tumor driven by subpopulations of cancer stem cells (CSCs). We recently used patient-derived organoids (PDOs) to demonstrate that CSC survival is regulated by autocrine non-canonical Hedgehog signaling, which acts as a positive regulator of Wnt signaling to block CSC...
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| Publicado en: | Mol Cell Oncol |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149873/ https://ncbi.nlm.nih.gov/pubmed/30250897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1445940 |
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