Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies

Human African Trypanosomiasis (HAT), a disease that provokes 2184 new cases a year in Sub-Saharan Africa, is caused by Trypanosoma brucei. Current treatments are limited, highly toxic, and parasite strains resistant to them are emerging. Therefore, there is an urgency to find new drugs against HAT....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Vázquez-Raygoza, Alejandra, Cano-González, Lucia, Velázquez-Martínez, Israel, Trejo-Soto, Pedro Josué, Castillo, Rafael, Hernández-Campos, Alicia, Hernández-Luis, Francisco, Oria-Hernández, Jesús, Castillo-Villanueva, Adriana, Avitia-Domínguez, Claudia, Sierra-Campos, Erick, Valdez-Solana, Mónica, Téllez-Valencia, Alfredo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149853/
https://ncbi.nlm.nih.gov/pubmed/29186784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122055
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky