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Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy

Selective clearance of damaged mitochondria can reverse pathological status in chronic inflammatory diseases. We recently identified a critical role of nuclear receptor Nur77 and celastrol in priming inflamed mitochondria for autophagy through its mitochondrial targeting and interaction with tumor n...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Hu, Mengjie, Alitongbieke, Gulimiran, Su, Ying, Zhou, Hu, Zhang, Xiao-kun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149810/
https://ncbi.nlm.nih.gov/pubmed/30250883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1327005
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