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How Many Drugs Are Catecholics

By examination of the 8659 drugs recorded in the Comprehensive Medicinal Chemistry (CMC) database, 78 catecholics (including five pyrogallolics) were identified, of which 17 are currently prescribed by FDA. Through analyzing the substitutent patterns, ClogPs and O-H bond dissociation enthalpies (BDE...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Yang, Da-Peng, Ji, Hong-Fang, Tang, Guang-Yan, Ren, Wei, Zhang, Hong-Yu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149448/
https://ncbi.nlm.nih.gov/pubmed/17851440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12040878
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