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The unc-53 gene negatively regulates rac GTPases to inhibit unc-5 activity during Distal tip cell migrations in C. elegans

The unc-53/NAV2 gene encodes for an adaptor protein required for cell migrations along the anteroposterior (AP) axes of C. elegans. This study identifies unc-53 as a novel component of signaling pathways regulating Distal tip cell (DTC) migrations along the AP and dorsoventral (DV) axes. unc-53 nega...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Pandey, Amita, Yadav, Vipul, Sharma, Aditi, Khurana, Jitendra P., Pandey, Girdhar K.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149439/
https://ncbi.nlm.nih.gov/pubmed/28678595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2017.1345413
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