Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory

Group I metabotropic glutamate receptors, in particular mGluR5, have been implicated in various forms of synaptic plasticity that are believed to underlie declarative memory. We observed that mGluR5 specifically activated a channel containing TRPC1, an isoform of the canonical family of transient re...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Lepannetier, Sophie, Gualdani, Roberta, Tempesta, Sabrina, Schakman, Olivier, Seghers, François, Kreis, Anna, Yerna, Xavier, Slimi, Amina, de Clippele, Marie, Tajeddine, Nicolas, Voets, Thomas, Bon, Robin S., Beech, David J., Tissir, Fadel, Gailly, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149316/
https://ncbi.nlm.nih.gov/pubmed/30271326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00318
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