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Synthesis and Bioevaluation of 5-Fluorouracil Derivatives

A series of six novel 5-fluorouracil derivatives 1-6 were synthesized and their structures confirmed by (1)H- and (13)C-NMR, MS and elemental analysis. The preliminary in vitro antitumor activities against B16, K562 and CHO cells and the in vivo inhibitions of liver cancer H(22) demonstrated that so...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tian, Zhi-Yong, Du, Gang-Jun, Xie, Song-Qiang, Zhao, Jin, Gao, Wen-Yuan, Wang, Chao-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149112/
https://ncbi.nlm.nih.gov/pubmed/18065949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/12112450
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