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Two Half-Sandwiched Ruthenium (II) Compounds Containing 5-Fluorouracil Derivatives: Synthesis and Study of DNA Intercalation

Two novel coordination compounds of half-sandwiched ruthenium(II) containing 2-(5-fluorouracil)-yl-N-(pyridyl)-acetamide were synthesized, and their intercalation binding modes with calf thymus DNA were revealed by hyperchromism of ultraviolet-visible spectroscopy; the binding constants were determi...

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Publicat a:PLoS One
Autors principals: Li, Zhao-Jun, Hou, Yong, Qin, Da-An, Jin, Zhi-Min, Hu, Mao-Lin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366203/
https://ncbi.nlm.nih.gov/pubmed/25789618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120211
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