Hypoxia promotes the migration and invasion of human hepatocarcinoma cells through the HIF-1α–IL-8–Akt axis

BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer-related death worldwide. The 5-year survival rate remains low despite considerable research into treatments of HCC, including surgery, radiotherapy and chemotherapy. Many mechanisms w...

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Veröffentlicht in:Cell Mol Biol Lett
Hauptverfasser: Fei, Maoyun, Guan, Jianming, Xue, Tao, Qin, Lianjin, Tang, Chengwu, Cui, Ge, Wang, Yao, Gong, Hui, Feng, Wenming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Short Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149064/
https://ncbi.nlm.nih.gov/pubmed/30258464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0100-6
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