HIF-1α promotes the migration and invasion of hepatocellular carcinoma cells via the IL-8–NF-κB axis

BACKGROUND: Hypoxia plays a critical role in many cancers. Hypoxia inducible factor-1α (HIF-1α) is an important mediator of the hypoxia response. It regulates the expression of various chemokines involved in tumor growth, angiogenesis and metastasis but the associated pathway needs further investiga...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Feng, Wenming, Xue, Tao, Huang, Sanxiong, Shi, Qilin, Tang, Chengwu, Cui, Ge, Yang, Guanghui, Gong, Hui, Guo, Huihui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984319/
https://ncbi.nlm.nih.gov/pubmed/29881400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0077-1
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