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HIF-1α promotes the migration and invasion of hepatocellular carcinoma cells via the IL-8–NF-κB axis
BACKGROUND: Hypoxia plays a critical role in many cancers. Hypoxia inducible factor-1α (HIF-1α) is an important mediator of the hypoxia response. It regulates the expression of various chemokines involved in tumor growth, angiogenesis and metastasis but the associated pathway needs further investiga...
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| Pubblicato in: | Cell Mol Biol Lett |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984319/ https://ncbi.nlm.nih.gov/pubmed/29881400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0077-1 |
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