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MicroRNA199a-Based Post-transcriptional Detargeting of Gene Vectors for Hepatocellular Carcinoma

A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be constructed either by targeting HCC or by detargetin...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Dhungel, Bijay, Ramlogan-Steel, Charmaine A., Layton, Christopher J., Steel, Jason C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148835/
https://ncbi.nlm.nih.gov/pubmed/30245470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.016
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