A Convenient Asymmetric Synthesis of a β-amino Ester with Additional Functionalization as a Precursor for Peptide Nucleic Acid (PNA) Monomers

We report the asymmetric synthesis of di-3-pentyl (3S,αS,7E)-3-N-benzyl-N-α-methylbenzylamino-dec-7-enedioate (9), which contains the correct functionalization to produce δ-amino acid derivatives to be used as monomers for Peptide Nucleic Acid (PNA) formation With this aim, thymine-pentanoic acid 15...

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Foilsithe in:Molecules
Main Authors: Garrido, Narciso M., Díez, David, Domínguez, Sara H., Sánchez, M. Rosa, García, Mercedes, Urones, Julio G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2006
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148629/
https://ncbi.nlm.nih.gov/pubmed/17962776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11060435
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