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First Synthesis of 3-Acetyl-2-aminothiophenes Using the Gewald Reaction

Novel 3-acetyl-2-aminothiophenes were prepared from cyanoacetone and 1,4‑dithianyl-2,5‑diols using a modified Gewald reaction. The syntheses of the corresponding acetamides, as well as that of 3‑acetyl-2‑amino-5‑nitrothiophene – an interesting building-block for thiophene azo dyes – are reported. De...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Eller, Gernot A., Holzer, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148543/
https://ncbi.nlm.nih.gov/pubmed/17962769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11050371
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