An Efficient Synthesis of a Spirocyclic Oxindole Analogue

An efficient, scaleable synthesis approach towards the spirocyclic oxindole analogue 1’-(tert-butoxycarbonyl)-2-oxospiro[indoline-3,4’-piperidine]-5-carboxylic acid (1) is described. The key steps are dianion alkylation and cyclization of ethyl 2-oxindoline-5-carboxylate (4) and demethylation of the...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Teng, Dawei, Zhang, Hongxing, Mendonca, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2006
Konular:
Full Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148541/
https://ncbi.nlm.nih.gov/pubmed/17971744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11090700
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