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An Efficient Synthesis of a Spirocyclic Oxindole Analogue
An efficient, scaleable synthesis approach towards the spirocyclic oxindole analogue 1’-(tert-butoxycarbonyl)-2-oxospiro[indoline-3,4’-piperidine]-5-carboxylic acid (1) is described. The key steps are dianion alkylation and cyclization of ethyl 2-oxindoline-5-carboxylate (4) and demethylation of the...
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| Published in: | Molecules |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148541/ https://ncbi.nlm.nih.gov/pubmed/17971744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11090700 |
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