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Synthesis and Biological Evaluation of New 4β-5-Fu-substituted 4(')-Demethylepipodophyllotoxin Derivatives

A series of new 4β-5-Fu-substituted 4(')-demethylepipodophyllotoxin derivatives were synthesized and evaluated, together with some previously prepared ones, for their cytotoxic activities against four tumor cell lines (HL60, P388, A549 and BEL7402). Three of these compounds exhibited superior i...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Fu-Min, Yao, Xiao-Jun, Tian, Xuan, Tu, Yong-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148536/
https://ncbi.nlm.nih.gov/pubmed/18007391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11110849
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