Synthesis and Structural Characterization of 1- and 2-Substituted Indazoles: Ester and Carboxylic Acid Derivatives

A series of indazoles substituted at the N-1 and N-2 positions with ester- containing side chains -(CH(2))(n)CO(2)R of different lengths (n = 0-6, 9, 10) are described. Nucleophilic substitution reactions on halo esters (X(CH(2))(n)CO(2)R) by 1H-indazole in alkaline solution lead to mixtures of N-1...

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Veröffentlicht in:Molecules
Hauptverfasser: Teixeira, Fátima C., Ramos, Hélène, Antunes, Inês F., Curto, M. João M., Teresa Duarte, M., Bento, Isabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148532/
https://ncbi.nlm.nih.gov/pubmed/18007393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/11110867
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