Development of subnanomolar-affinity serotonin 5-HT(4) receptor ligands based on quinoline structures

Two small series of quinoline derivatives were designed starting from previously published quinoline derivatives 7a and b in order to obtain information about their interaction with the 5-HT(4)R binding site. Initially, the structure of 7a and b was modified by replacing their basic moiety with that...

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Dades bibliogràfiques
Publicat a:Medchemcomm
Autors principals: Castriconi, Federica, Paolino, Marco, Grisci, Giorgio, Francini, Cinzia Maria, Reale, Annalisa, Giuliani, Germano, Anzini, Maurizio, Giorgi, Gianluca, Mennuni, Laura, Sabatini, Chiara, Lanza, Marco, Caselli, Gianfranco, Cappelli, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148519/
https://ncbi.nlm.nih.gov/pubmed/30288221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00233a
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