Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype

X-chromosome inactivation (XCI) is an essential epigenetic process in female mammalian development. Although cell-based studies suggest the potential importance of the Ftx long non-protein-coding RNA (lncRNA) in XCI, its physiological roles in vivo remain unclear. Here we show that targeted deletion...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hosoi, Yusuke, Soma, Miki, Shiura, Hirosuke, Sado, Takashi, Hasuwa, Hidetoshi, Abe, Kuniya, Kohda, Takashi, Ishino, Fumitoshi, Kobayashi, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148026/
https://ncbi.nlm.nih.gov/pubmed/30237402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06327-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados