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Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

Phosphorylation of Pseudomonas aeruginosa lipopolysaccharide (LPS) is important for maintaining outer membrane integrity and intrinsic antibiotic resistance. We solved the crystal structure of the LPS heptose kinase WaaP, which is essential for growth of P. aeruginosa. WaaP was structurally similar...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147952/
https://ncbi.nlm.nih.gov/pubmed/30237436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32379-1
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