Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

Phosphorylation of Pseudomonas aeruginosa lipopolysaccharide (LPS) is important for maintaining outer membrane integrity and intrinsic antibiotic resistance. We solved the crystal structure of the LPS heptose kinase WaaP, which is essential for growth of P. aeruginosa. WaaP was structurally similar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147952/
https://ncbi.nlm.nih.gov/pubmed/30237436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32379-1
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