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Epac1 protects the retina against ischemia/reperfusion-induced neuronal and vascular damage

We had previously reported that exchange protein for cAMP 1 (Epac1) reduced inflammatory mediators in the retina of mice and in retinal endothelial cells (REC). Since ischemia can induce retinal damage potentially through activation of inflammatory cascades, we hypothesized that Epac1 would protect...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Liu, Li, Jiang, Youde, Steinle, Jena J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147720/
https://ncbi.nlm.nih.gov/pubmed/30235337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204346
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