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Epac1 protects the retina against ischemia/reperfusion-induced neuronal and vascular damage

We had previously reported that exchange protein for cAMP 1 (Epac1) reduced inflammatory mediators in the retina of mice and in retinal endothelial cells (REC). Since ischemia can induce retinal damage potentially through activation of inflammatory cascades, we hypothesized that Epac1 would protect...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Liu, Li, Jiang, Youde, Steinle, Jena J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147720/
https://ncbi.nlm.nih.gov/pubmed/30235337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204346
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