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Epac1 protects the retina against ischemia/reperfusion-induced neuronal and vascular damage

We had previously reported that exchange protein for cAMP 1 (Epac1) reduced inflammatory mediators in the retina of mice and in retinal endothelial cells (REC). Since ischemia can induce retinal damage potentially through activation of inflammatory cascades, we hypothesized that Epac1 would protect...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Li, Jiang, Youde, Steinle, Jena J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147720/
https://ncbi.nlm.nih.gov/pubmed/30235337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204346
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