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Prions activate a p38 MAPK synaptotoxic signaling pathway
Synaptic degeneration is one of the earliest pathological correlates of prion disease, and it is a major determinant of the progression of clinical symptoms. However, the cellular and molecular mechanisms underlying prion synaptotoxicity are poorly understood. Previously, we described an experimenta...
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| Vydáno v: | PLoS Pathog |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6147624/ https://ncbi.nlm.nih.gov/pubmed/30235355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007283 |
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