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Comparative Studies of the Effects of Two Novel Sugar Drug Candidates on the CYP 1A2 CYP 2E1 Enzymes in Different Sexed Rats Using a “Cocktail” Approach

The sex-based differences between the effects of two novel sugar-based drug candidates, a sulfated polymannuroguluronate (SPMG-911) and an acidic oligosaccharide sugar chain compound (AOSC-971), on the enzymes CYP 1A2 and CYP 2E1 were investigated. The results showed that neither SPMG-911 nor AOSC-9...

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Publicado en:Molecules
Autores principales: Shi, Jie, Geng, Mei-Yu, Liu, Chang-Xiao
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147348/
https://ncbi.nlm.nih.gov/pubmed/18007498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/91100978
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