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PPARγ Deficiency Suppresses the Release of IL-1β and α in Macrophages via a Type 1 Interferon Dependent Mechanism
Obesity and diabetes modulate macrophage activation often leading to prolonged inflammation and dysfunctional tissue repair. Increasing evidence suggests that the NLRP3 inflammasome plays an important role in obesity-associated inflammation. We have previously shown that activation of the lipotoxic...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6147147/ https://ncbi.nlm.nih.gov/pubmed/30143592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800224 |
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