Asymmetric Synthesis of (R)‐1‐Alkyl‐Substituted Tetrahydro‐ß‐carbolines Catalyzed by Strictosidine Synthases

Stereoselective methods for the synthesis of tetrahydro‐ß‐carbolines are of significant interest due to the broad spectrum of biological activity of the target molecules. In the plant kingdom, strictosidine synthases catalyze the C−C coupling through a Pictet–Spengler reaction of tryptamine and seco...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Pressnitz, Desiree, Fischereder, Eva‐Maria, Pletz, Jakob, Kofler, Christina, Hammerer, Lucas, Hiebler, Katharina, Lechner, Horst, Richter, Nina, Eger, Elisabeth, Kroutil, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146909/
https://ncbi.nlm.nih.gov/pubmed/29852524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201803372
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