A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV

The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) continues to infect humans and camels, calling for efficient, cost-effective, and broad-spectrum strategies to control its spread. Nanobodies (Nbs) are single-domain antibodies derived from camelids and sharks and are potentia...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhao, Guangyu, He, Lei, Sun, Shihui, Qiu, Hongjie, Tai, Wanbo, Chen, Jiawei, Li, Jiangfan, Chen, Yuehong, Guo, Yan, Wang, Yufei, Shang, Jian, Ji, Kaiyuan, Fan, Ruiwen, Du, Enqi, Jiang, Shibo, Li, Fang, Du, Lanying, Zhou, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146697/
https://ncbi.nlm.nih.gov/pubmed/29950421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00837-18
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