Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry

Protection against acquiring human immunodeficiency virus (HIV) infection may not require a vaccine in the conventional sense, because broadly neutralizing antibodies (bNAbs) alone prevent HIV infection in relevant animal challenge models. Additionally, bNAbs as therapeutics can effectively suppress...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Khan, Salar N., Sok, Devin, Tran, Karen, Movsesyan, Arlette, Dubrovskaya, Viktoriya, Burton, Dennis R., Wyatt, Richard T.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146690/
https://ncbi.nlm.nih.gov/pubmed/29976677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00384-18
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