PARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type

Epstein Barr virus (EBV) is a potentially oncogenic gammaherpesvirus that establishes a chronic, latent infection in memory B cells. The EBV genome persists in infected host cells as a chromatinized episome and is subject to chromatin-mediated regulation. Binding of the host insulator protein CTCF t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lupey-Green, Lena N., Caruso, Lisa B., Madzo, Jozef, Martin, Kayla A., Tan, Yinfei, Hulse, Michael, Tempera, Italo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146685/
https://ncbi.nlm.nih.gov/pubmed/29976663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-18
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