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Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1

The latent infection of Epstein-Barr virus (EBV) is associated with 1% of human cancer incidence. Poly(ADP-ribosyl)ation (PARylation) is a posttranslational modification catalyzed by poly(ADP-ribose) polymerases (PARPs) that mediate EBV replication during latency. In this study, we detail the mechan...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Martin, Kayla A., Lupey, Lena N., Tempera, Italo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021435/
https://ncbi.nlm.nih.gov/pubmed/27440880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01180-16
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