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Synthesis of New Lipophilic Phosphonate and Phosphonamidate Analogues of N-Acetylmuramyl-L-alanyl-D-isoglutamine Related to LK 423

A syntheses of three new muramyl dipeptide (MDP) analogues related to LK 423 as potential immunomodulators are presented. The dipeptide part of the lead compound was modified by introducing a phosphonamide isostere instead of the amide bond between L-alanine and D-glutamic acid (or D-isoglutamine),...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Gobec, Stanislav, Urleb, Uroš
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146478/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/70400394
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