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RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis

Individuals with diverticula or outpouchings of the colonic mucosa and submucosa through the colonic wall have diverticulosis, which is usually asymptomatic. In 10-25% of individuals, the diverticula become inflamed, resulting in diverticulitis. Very little is known about the pathophysiology or gene...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Schieffer, Kathleen M., Choi, Christine S., Emrich, Scott, Harris, Leonard, Deiling, Sue, Karamchandani, Dipti M., Salzberg, Anna, Kawasawa, Yuka I., Yochum, Gregory S., Koltun, Walter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146301/
https://ncbi.nlm.nih.gov/pubmed/28619727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00136.2017
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