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The rebirth of iPSCs: Towards a healthier epigenetic landscape

It is well recognized that transcription factor-induced iPSCs carry an aberrant genetic and epigenetic makeup. However, it is not clear whether these defects are developed de novo due to the reprogramming process or inherited from the somatic source cells. Ma and colleagues presented convincing data...

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Detalles Bibliográficos
Publicado en:Genes Dis
Autor Principal: Li, Fei
Formato: Artigo
Idioma:Inglês
Publicado: Chongqing Medical University 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146140/
https://ncbi.nlm.nih.gov/pubmed/30258858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2014.08.002
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