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The rebirth of iPSCs: Towards a healthier epigenetic landscape

It is well recognized that transcription factor-induced iPSCs carry an aberrant genetic and epigenetic makeup. However, it is not clear whether these defects are developed de novo due to the reprogramming process or inherited from the somatic source cells. Ma and colleagues presented convincing data...

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Vydáno v:Genes Dis
Hlavní autor: Li, Fei
Médium: Artigo
Jazyk:Inglês
Vydáno: Chongqing Medical University 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146140/
https://ncbi.nlm.nih.gov/pubmed/30258858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2014.08.002
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