Processive chitinase is Brownian monorail operated by fast catalysis after peeling rail from crystalline chitin

Processive chitinase is a linear molecular motor which moves on the surface of crystalline chitin driven by processive hydrolysis of single chitin chain. Here, we analyse the mechanism underlying unidirectional movement of Serratia marcescens chitinase A (SmChiA) using high-precision single-molecule...

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Udgivet i:Nat Commun
Main Authors: Nakamura, Akihiko, Okazaki, Kei-ichi, Furuta, Tadaomi, Sakurai, Minoru, Iino, Ryota
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145945/
https://ncbi.nlm.nih.gov/pubmed/30232340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06362-3
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