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Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease

Previous studies have demonstrated that temporarily increasing the permeability of the blood-brain barrier using focused ultrasound can reduce β-amyloid plaque load and improve cognitive function in animal models of Alzheimer’s disease. However, the underlying mechanism and duration for which the ef...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Poon, Charissa T., Shah, Kairavi, Lin, Chiungting, Tse, Ryan, Kim, Kate K., Mooney, Skyler, Aubert, Isabelle, Stefanovic, Bojana, Hynynen, Kullervo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145880/
https://ncbi.nlm.nih.gov/pubmed/30232364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32250-3
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