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NKG2D and its ligands in cancer

NKG2D is an activating immune receptor expressed by NK and effector T cells. Induced expression of NKG2D ligand on tumor cell surface during oncogenic insults renders cancer cells susceptible to immune destruction. In advanced human cancers, tumor cells shed NKG2D ligand to produce an immune soluble...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Immunol
Main Authors: Dhar, Payal, Wu, Jennifer D
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145810/
https://ncbi.nlm.nih.gov/pubmed/29525346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.02.004
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