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NKG2D and its ligands in cancer
NKG2D is an activating immune receptor expressed by NK and effector T cells. Induced expression of NKG2D ligand on tumor cell surface during oncogenic insults renders cancer cells susceptible to immune destruction. In advanced human cancers, tumor cells shed NKG2D ligand to produce an immune soluble...
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| Udgivet i: | Curr Opin Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6145810/ https://ncbi.nlm.nih.gov/pubmed/29525346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.02.004 |
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